پاسخ سیستم ایمنی بدن ناشی از ورزش
ترجمه نشده

پاسخ سیستم ایمنی بدن ناشی از ورزش

عنوان فارسی مقاله: پاسخ سیستم ایمنی بدن ناشی از ورزش: وضعیت ضد التهابی در اندامهای محیطی و مرکزی
عنوان انگلیسی مقاله: Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs
مجله/کنفرانس: اساس مولکولی بیماری - BBA - Molecular Basis of Disease
رشته های تحصیلی مرتبط: تربیت بدنی
گرایش های تحصیلی مرتبط: فیزیولوژی ورزشی، فیزیولوژی فعالیت بدنی و تندرستی، فیزیولوژی فعالیت ورزشی بالینی
کلمات کلیدی فارسی: التهاب، فعالیت بدنی، حفاظت نورونی، بیماریهای مزمن واگیر، بیماریهای مزمن غیرواگیر، بیومارکر
کلمات کلیدی انگلیسی: inflammation، physical exercise، neuroprotection، communicable chronic diseases، non-communicable chronic diseases، biomarker
نوع نگارش مقاله: مقاله مروری (Review Article)
شناسه دیجیتال (DOI): https://doi.org/10.1016/j.bbadis.2020.165823
دانشگاه: Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil
صفحات مقاله انگلیسی: 47
ناشر: الزویر - Elsevier
نوع ارائه مقاله: ژورنال
نوع مقاله: ISI
سال انتشار مقاله: 2020
ایمپکت فاکتور: 4/279 در سال 2019
شاخص H_index: 128 در سال 2020
شاخص SJR: 1/843 در سال 2019
شناسه ISSN: 0925-4439
شاخص Quartile (چارک): Q1 در سال 2019
فرمت مقاله انگلیسی: PDF
وضعیت ترجمه: ترجمه نشده است
قیمت مقاله انگلیسی: رایگان
آیا این مقاله بیس است: خیر
آیا این مقاله مدل مفهومی دارد: ندارد
آیا این مقاله پرسشنامه دارد: ندارد
آیا این مقاله متغیر دارد: ندارد
کد محصول: E14924
رفرنس: دارای رفرنس در داخل متن و انتهای مقاله
فهرست مطالب (انگلیسی)

Abstract

1- Introduction

2- Material and methods

3- Definition of physical exercise

4- Immune system modulation by the practice of physical exercise

5- Anti-inflammatory effects of physical exercise

6- Physical exercise as a non-pharmacological intervention for neuroprotection

7- Physical exercise and neopterin

8- Physical exercise and inflammation-induced pain: Relevance of BH4

9- Summary and future directions

References

بخشی از مقاله (انگلیسی)

Abstract

A wide array of molecular pathways has been investigated during the past decade in order to understand the mechanisms by which the practice of physical exercise promotes neuroprotection and reduces the risk of developing communicable and non-communicable chronic diseases. While a single session of physical exercise may induce a transient imbalance of cell homeostasis, repeated physical exercise sessions will improve immunosurveillance and immunocompetence. Additionally, immune cells from the central nervous system will acquire an anti-inflammatory phenotype, protecting central functions from age-induced cognitive decline. This review highlights the exercise-induced anti-inflammatory effect on the prevention or treatment of common chronic clinical and experimental settings. It also suggests the use of pterins in biological fluids as sensitive biomarkers to follow the anti-inflammatory effect of physical exercise.

Introduction

The practice of physical activity and/or physical exercise is an efficient free -drug strategy for the prevention and treatment of several chronic diseases. A great body of scientific evidence has contributed to establish a positive correlation between a physically active lifestyle and health benefits [1]. According to the Physical Activity Guidelines for Americans, individuals affected by chronic diseases should practice a minimum of 150 mi n per week of moderate -intensity exercise, or at least 75 min per week of vigorous -intensity aerobic physical activity to improve health [2] . Additional health benefits can also be promoted by performing muscle -strengthening activities involving all main muscle groups at least twice a week [2] . Due to enhanced musculoskeletal function, cardiorespiratory and metabolic health, sleep, pain management, cognition, learning, memory and more, the practice of physical exercise represents a non-pharmacological primary clinical tool for the prevention of many diseases whose physiopathology is linked to acute or sustained immune system activation [3 –5]. In general repeated moderate intensity exercise enhances the immune function response, reinforces the antioxidative capacity, reduces oxidative stress, and increases the efficiency of energy generation , therefore reducing the incidence of inflammatory diseases [6,7] . Acute bouts of physical exercise also regulate the immune response, i.e. by transiently redistributing immune cells to peripheral tissues, resulting in a heightened state of immun ocompetence [8] .