یافته های یک کلینیک در مورد تشخیص اختلال دوقطبی در چندابتلایی بیماران
ترجمه نشده

یافته های یک کلینیک در مورد تشخیص اختلال دوقطبی در چندابتلایی بیماران

عنوان فارسی مقاله: اختلالات اضطرابی تشخیص اختلال دوقطبی در چندابتلایی بیماران را پیش بینی می کند: یافته های یک کلینیک عالی ایتالیا
عنوان انگلیسی مقاله: Anxiety disorders anticipate the diagnosis of bipolar disorder in comorbid patients: Findings from an Italian tertiary clinic
مجله/کنفرانس: مجله اختلالات عاطفی - Journal of Affective Disorders
رشته های تحصیلی مرتبط: روانشناسی، پزشکی
گرایش های تحصیلی مرتبط: روانشناسی بالینی، روانپزشکی
کلمات کلیدی فارسی: اختلال دو قطبی (BD)، اختلال اضطراب (AD)، هجوم، شیوع، خصوصیات بالینی
کلمات کلیدی انگلیسی: Bipolar disorder (BD)، Anxiety disorder (AD)، Onset، Prevalence، Clinical characterization
نوع نگارش مقاله: مقاله پژوهشی (Research Article)
نمایه: Scopus - Master Journals List - MedLine - JCR
شناسه دیجیتال (DOI): https://doi.org/10.1016/j.jad.2019.07.033
دانشگاه: Department of Psychiatry, Department of Biomedical and Clinical Sciences “Luigi Sacco”, University of Milan, ASST Fatebenefratelli-Sacco, Via G.B. Grassi 74, 20157 Milan, Italy
صفحات مقاله انگلیسی: 6
ناشر: الزویر - Elsevier
نوع ارائه مقاله: ژورنال
نوع مقاله: ISI
سال انتشار مقاله: 2019
ایمپکت فاکتور: 4/165 در سال 2018
شاخص H_index: 165 در سال 2019
شاخص SJR: 1/873 در سال 2018
شناسه ISSN: 0165-0327
شاخص Quartile (چارک): Q1 در سال 2018
فرمت مقاله انگلیسی: PDF
وضعیت ترجمه: ترجمه نشده است
قیمت مقاله انگلیسی: رایگان
آیا این مقاله بیس است: خیر
آیا این مقاله مدل مفهومی دارد: ندارد
آیا این مقاله پرسشنامه دارد: ندارد
آیا این مقاله متغیر دارد: دارد
کد محصول: E12656
رفرنس: دارای رفرنس در داخل متن و انتهای مقاله
فهرست مطالب (انگلیسی)

Abstract

Introduction

Methods

Results

Discussion

References

بخشی از مقاله (انگلیسی)

Abstract

Background: Studies indicate bipolar disorder (BD) syndromal symptoms are commonly preceded by sub-syndromal BD symptoms, dysregulated sleep, irritability, and anxiety. We aimed to evaluate prevalence and clinical correlates of anxiety disorders (ADs) at BD onset in outpatients with versus without at least one AD at BD onset. Methods: 246 bipolar spectrum outpatients, according to the text revision of the fourth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM- IV-TR), attending Sacco University Hospital in Milan, were recruited and their onset and clinical features assessed retrospectively. Patients were stratified into those with versus without an AD at BD onset (w/A and wo/A), according to a semistructured clinical interview to provide diagnoses according to (DSM- IV-TR).

Results: 29% of patients reported being w/A, among whom Panic Disorder (PD, in 55.6%) was the most frequent AD, and first AD occurred approximately 4 years before BD diagnosis. Patients w/A versus wo/A had higher (p < 0.05) rates of BDII and first mood episode being depression versus elevation (mania/hypomania), and lifetime rates of separation anxiety disorder, substance poly-abuse and benzodiazepine abuse. In contrast, patients wo/A had higher lifetime rates of alcohol and illicit drug use. Conclusion: In this naturalistic sample, ADs, in particular PD, preceded BD in almost 1/3 of BD outpatients, and had distinctive clinical correlates. Further investigation into relationships between BD and AD at onset may enhance early BD diagnosis and treatment.

Introduction

Bipolar disorder (BD) is a highly disabling condition affecting about 1.5% of the general population globally (Kendall et al., 2014) and responsible for 1.3% of total years lived with disability and 0.4% of total disability-adjusted life years worldwide (Ferrari et al., 2016). BD is characterized by different and complex clinical features over its longitudinal course, including recurrent mood episodes, comorbid psychiatric and medical problems, progressive social and cognitive impairment and, ultimately, much higher suicide/suicide attempt risks, compared to the general population (Cremaschi et al., 2017; Simon et al., 2007) Indeed, BD is frequently associated with other psychiatric comorbid conditions, in particular anxiety disorders (ADs) (Nabavi et al., 2015) and substance use disorders (Gold et al., 2018). Epidemiologic and clinical studies report lifetime rates of development of at least one AD over the longitudinal course of BD ranging between 39% and 55% (Vázquez et al., 2014).