دانلود مقاله پذیرش واکسن کووید-19 در کودکی از سوی کارکنان مراقبت بهداشتی
خلاصه
1. مقدمه
2. روش
3. نتایج
4. بحث
5. نتیجه گیری
مشارکت های نویسنده
تامین مالی/حمایت
به اشتراک گذاری داده ها
اعلامیه منافع رقابتی
پیوست A. داده های تکمیلی
منابع
Abstract
1. Introduction
2. Method
3. Results
4. Discussion
5. Conclusion
Author contributions
Funding/Support
Data sharing
Declaration of Competing Interest
Appendix A. Supplementary data
References
چکیده
با تأیید بیشتر واکسن‌های COVID-19 برای کودکان، ویژگی‌های واکسن ممکن است بر پذیرش و انتخاب والدین تأثیر بگذارد. هدف ما ارزیابی اثرات ویژگی‌های واکسن و اطلاعات بر ایمنی گله در پذیرش واکسن کووید-19 در دوران کودکی بود. یک آزمایش نظرسنجی با مراقبان کودکان 6 ماهه تا 11 ساله و کارکنان مراقبت های بهداشتی (HCWs) در چین از 14 سپتامبر تا 18 نوامبر 2021 انجام شد. پاسخ دهندگان به طور تصادفی برای دریافت اطلاعات متفاوت در مورد ایمنی گله (بیش از 80٪) تقسیم شدند. کل جمعیت باید واکسینه شوند؛ یا هیچ اطلاعاتی وجود ندارد). سپس پاسخ دهندگان هشت وظیفه انتخاب گسسته را برای ارزیابی پذیرش واکسن بر اساس ویژگی ها تکمیل کردند. 2331 (90.07%) از 2588 مراقب مورد بررسی و 1576 (92.71%) از 1700 HCW مورد بررسی به ترتیب واکسیناسیون کووید-19 را برای کودکان می پذیرند. نسبت شانس بالا (OR) برای پذیرش واکسنی با اثربخشی 90% بیش از 50% یافت شد (OR 6.70 [95% فاصله اطمینان (CI): 6.11-7.35] برای مراقبان؛ 11.44 [10.12-12.95] برای HCWs). و خطر عوارض جانبی 1 روی 10 در 10000 باشد (3.96 [3.72-4.22] برای مراقبان؛ 2.98 [2.76-3.22] برای HCWs). برای دستیابی به هدف ایمنی گله (بیش از 80 درصد پوشش واکسیناسیون)، اثربخشی واکسن باید به بیش از 70 درصد برسد و خطر عوارض جانبی کمتر از 1 در 10000 باشد. دانش در مورد هدف ایمنی گله، شانس پذیرش واکسن را افزایش داد (1.82 [1.34-2.46] برای مراقبان؛ 2.42 [1.58-3.72] برای HCWs). پذیرش واکسن کووید-19 در دوران کودکی، مستقل از سن کودک، در چین بالا بود و به ویژگی‌های واکسن بستگی داشت.
توجه! این متن ترجمه ماشینی بوده و توسط مترجمین ای ترجمه، ترجمه نشده است.
Abstract
With approval of more COVID-19 vaccines for children, vaccine attributes may influence parental acceptance and choices. We aimed to assess effects of vaccine attributes and information on herd immunity on childhood COVID-19 vaccine acceptance. A survey experiment was conducted with caregivers of children aged 6 months to 11 years old and health care workers (HCWs) in China from September 14 to November 18, 2021. Respondents were randomly assigned to receive differing information on herd immunity (> 80% of the entire population must be vaccinated; or no information). Respondents then completed eight discrete choice tasks to assess vaccine acceptance based on attributes. 2331 (90.07%) of 2588 surveyed caregivers and 1576 (92.71%) of 1700 surveyed HCWs would accept COVID-19 vaccination for children, respectively. High Odds Ratios (OR) were found for acceptance of a vaccine with 90% over 50% efficacy (OR 6.70 [95% CI 6.11–7.35] for caregivers; 11.44 [10.12–12.95] for HCWs); and risk of adverse reactions to be 1 over 10 in 10,000 (3.96 [3.72–4.22] for caregivers; 2.98 [2.76–3.22] for HCWs). To achieve herd immunity target (> 80% vaccination coverage), vaccine efficacy should reach over 70% and risk of adverse reactions lower than 1 in 10,000. Knowledge on herd immunity target increased the odds of vaccine acceptance (1.82 [1.34–2.46] for caregivers; 2.42 [1.58–3.72] for HCWs). Childhood COVID-19 vaccine acceptance was high in China, independent of child's age, and depended on vaccine attributes.
Introduction
Vaccines are essential to control the global COVID-19 pandemic (Graham, 2020). Following widespread COVID-19 vaccination in adults and the elderly, vaccination of children and adolescents is recommended to protect them against COVID-19 (Nikolopoulou and Maltezou, 2022). In the United States, the COVID-19 vaccine was approved for emergency use in adolescents aged 12-to-15 years in May and children aged 5-to-11 years in October 2021 (FDA, 2021a, FDA, 2021b). In China, its emergency use was approved in children aged 3-to-17 years in June 2021 (The State Council of China, 2021a). China launched mass vaccination for children aged 12-to-17 years from late July, and for children aged 3-to-11 years from late October (The State Council of China, 2021b).
Parents may be more cautious about vaccinating their children than vaccinating themselves (Rane et al., 2022), especially when children appear to be less susceptible to COVID-19 than adults (Ludvigsson, 2020). A scoping review from 35 surveys found that, the median rate of parents' willingness to vaccinate their children against COVID-19 was 59.3% globally, lower than that for vaccinating themselves (Pan et al., 2021). Parental acceptance for childhood vaccination witnessed substantial variation across countries, ranging from 24% to 89% (Rane et al., 2022; Szilagyi et al., 2021; Bell et al., 2020; Kishore et al., 2021; Hetherington et al., 2021; Montalti et al., 2021; Aldakhil et al., 2021). Even in the same countries, parental acceptance of children's COVID-19 vaccines was significantly lower than their acceptance for routine childhood vaccines (Temsah et al., 2021).
Conclusion
In summary, this survey and DCE experiment show high acceptance of childhood COVID-19 vaccine among Chinese caregivers and HCWs, which was undifferentiated across children aged 6 months to 11 years. Vaccine acceptance depends on its attributes such as efficacy and safety. To achieve herd immunity target with above 80% vaccination coverage, the efficacy of COVID-19 vaccine should reach over 70% and the risk of adverse reactions should be lower than 1 in 10,000.